Jian Jin Selected Research

Infections

2/2024	METTL3 enhances E. coli F18 resistance by targeting IKBKG/NF-κB signaling via an m6A-YTHDF1-dependent manner in IPEC-J2 cells.
12/2023	USP2 inhibition prevents infection with ACE2-dependent coronaviruses in vitro and is protective against SARS-CoV-2 in mice.
11/2022	Comprehensive Analysis Revealed the Potential Roles of N6-Methyladenosine (m6A) Mediating E. coli F18 Susceptibility in IPEC-J2 Cells.
5/2022	m6A Demethylase ALKBH5 Restrains PEDV Infection by Regulating GAS6 Expression in Porcine Alveolar Macrophages.
1/2022	Insight into mechanisms of pig lncRNA FUT3-AS1 regulating E. coli F18-bacterial diarrhea.
2/2021	Porcine epidemic diarrhea virus infections induce autophagy in Vero cells via ROS-dependent endoplasmic reticulum stress through PERK and IRE1 pathways.
1/2020	Development of a PHMB hydrogel-modified wound scaffold dressing with antibacterial activity.
1/2019	Low-dose adefovir dipivoxil-induced hypophosphatemia osteomalacia in five chronic hepatitis B virus-infected patients. Is low-dose adefovir dipivoxil-induced nephrotoxicity completely reversible?
7/2018	Gut Microbial β-Glucuronidase Inhibition via Catalytic Cycle Interception.
1/2018	Influenza virus infection causes global RNAPII termination defects.

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Jian Jin Research Topics

Disease

134	Neoplasms (Cancer) 05/2024 - 08/2009
37	Breast Neoplasms (Breast Cancer) 01/2024 - 05/2006
19	Inflammation (Inflammations) 11/2023 - 01/2011
14	Infections 02/2024 - 03/2004
13	Fibrosis (Cirrhosis) 01/2023 - 08/2014
12	Carcinogenesis 01/2023 - 02/2014
9	Wounds and Injuries (Trauma) 04/2024 - 01/2015
9	Leukemia 04/2024 - 01/2013
9	Neoplasm Metastasis (Metastasis) 01/2023 - 09/2013
8	Multiple Myeloma 07/2023 - 02/2016
7	Diabetes Mellitus 03/2019 - 04/2013
6	Thyroid Neoplasms (Thyroid Cancer) 01/2024 - 01/2019
6	Triple Negative Breast Neoplasms 02/2023 - 04/2012
6	Ovarian Neoplasms (Ovarian Cancer) 11/2022 - 09/2013
6	Non-alcoholic Fatty Liver Disease 11/2021 - 04/2019
5	Lung Neoplasms (Lung Cancer) 04/2024 - 05/2018
5	COVID-19 03/2024 - 11/2020
5	Hepatocellular Carcinoma (Hepatoma) 01/2023 - 02/2016
5	Necrosis 01/2023 - 11/2018
5	Fatty Liver 01/2021 - 01/2019
5	Melanoma (Melanoma, Malignant) 01/2020 - 09/2008
4	Pain (Aches) 04/2024 - 05/2014
4	Pancreatic Neoplasms (Pancreatic Cancer) 12/2023 - 02/2015
4	Alzheimer Disease (Alzheimer's Disease) 11/2023 - 01/2021
4	Hypoxia (Hypoxemia) 02/2023 - 03/2015
4	Ureteral Obstruction 01/2023 - 12/2020
4	Mitochondrial Diseases (Mitochondrial Disease) 07/2022 - 01/2017
4	Colorectal Neoplasms (Colorectal Cancer) 01/2022 - 01/2015
4	Catalepsy 01/2021 - 11/2011
4	Hyperglycemia 01/2021 - 01/2016
4	Colonic Neoplasms (Colon Cancer) 08/2018 - 01/2014
3	Lymphopenia (Lymphocytopenia) 03/2024 - 11/2020
3	Stomach Neoplasms (Stomach Cancer) 02/2024 - 01/2018
3	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 02/2024 - 01/2021
3	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2024 - 01/2019
3	Heart Failure 03/2023 - 01/2014
3	Prostatic Neoplasms (Prostate Cancer) 10/2022 - 01/2014
3	Cicatrix (Scar) 07/2022 - 12/2018
3	Insulin Resistance 01/2021 - 03/2019

Drug/Important Bio-Agent (IBA)

52	Proteins (Proteins, Gene)FDA Link 03/2024 - 05/2006
20	Doxorubicin (Adriamycin)FDA LinkGeneric 10/2023 - 10/2012
15	ChromatinIBA 02/2024 - 09/2011
14	Histones (Histone)IBA 04/2024 - 08/2010
13	Lysine (L-Lysine)FDA Link 04/2024 - 08/2010
13	snake venom protein C activatorIBA 03/2024 - 01/2021
12	Biomarkers (Surrogate Marker)IBA 03/2024 - 04/2014
12	EnzymesIBA 12/2023 - 04/2018
11	Proteolysis Targeting ChimeraIBA 03/2024 - 01/2021
11	Phosphotransferases (Kinase)IBA 01/2023 - 09/2008
10	MethyltransferasesIBA 04/2024 - 01/2011
10	Paclitaxel (Taxol)FDA LinkGeneric 11/2022 - 09/2013
9	CytokinesIBA 10/2023 - 01/2014
8	Polycomb Repressive Complex 2IBA 07/2023 - 01/2015
8	Polychlorinated Biphenyls (PCBs)IBA 01/2021 - 01/2019
7	RNA (Ribonucleic Acid)IBA 12/2023 - 08/2017
7	LigandsIBA 01/2022 - 08/2012
7	Transcription Factors (Transcription Factor)IBA 01/2022 - 05/2006
7	Transient Receptor Potential ChannelsIBA 10/2017 - 10/2012
6	Histone MethyltransferasesIBA 03/2024 - 01/2014
6	CateninsIBA 01/2023 - 05/2015
6	MicroRNAs (MicroRNA)IBA 02/2022 - 05/2014
6	AnthracyclinesIBA 10/2018 - 10/2014
5	ProteomeIBA 03/2024 - 07/2020
5	Enhancer of Zeste Homolog 2 ProteinIBA 05/2023 - 01/2015
5	ErbB Receptors (EGF Receptor)IBA 01/2022 - 01/2014
5	Arginine (L-Arginine)FDA Link 01/2021 - 01/2011
5	taxaneIBA 10/2018 - 10/2014
5	Tacrolimus (Prograf)FDA LinkGeneric 01/2018 - 01/2016
5	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 03/2015 - 10/2012
4	Therapeutic UsesIBA 01/2024 - 08/2019
4	Oncogene Proteins (Oncogene Protein)IBA 10/2023 - 01/2022
4	Antipsychotic Agents (Antipsychotics)IBA 10/2023 - 11/2011
4	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 08/2023 - 01/2021
4	UNC1999IBA 05/2023 - 01/2015
4	ProdrugsIBA 02/2023 - 01/2018
4	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2023 - 01/2017
4	Small Interfering RNA (siRNA)IBA 01/2022 - 01/2017
4	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 07/2015
4	ElementsIBA 01/2021 - 07/2016
4	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 01/2021 - 12/2011
4	graphene oxideIBA 01/2021 - 01/2019
4	Phosphatidylinositols (Phosphatidylinositol)IBA 07/2019 - 05/2014
3	N-methyladenosineIBA 02/2024 - 05/2022
3	AntibodiesIBA 12/2023 - 04/2020
3	Dopamine (Intropin)FDA LinkGeneric 11/2023 - 12/2016
3	Proteasome Endopeptidase Complex (Proteasome)IBA 10/2023 - 08/2017
3	Photosensitizing Agents (Photosensitizers)IBA 02/2023 - 02/2022
3	AntigensIBA 01/2023 - 05/2006
3	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 11/2022 - 01/2019
3	Lapatinib (GW572016)FDA Link 01/2022 - 10/2012
3	DioxinsIBA 12/2021 - 04/2019
3	Antiviral Agents (Antivirals)IBA 10/2021 - 03/2004

Therapy/Procedure

67	Therapeutics 04/2024 - 04/2012
25	Drug Therapy (Chemotherapy) 02/2024 - 10/2012
5	Thyroidectomy 03/2022 - 01/2015
4	Oral Administration 11/2023 - 01/2015
4	Neoadjuvant Therapy 10/2022 - 04/2016
4	Transplantation 01/2021 - 01/2016
3	Immunotherapy 05/2024 - 01/2020
3	Radiotherapy 02/2024 - 07/2015